Tag Archives: cancer

Circulating Biomarkers Dundee 2014 a Success!

Circulating Biomarkers Dundee 2014 was a great success! The leadership of Ed Quazi and Elisabetta Fineschi of BioteXcel Ltd. made for a very productive two-day conference with many key leaders in the field from across the UK.  Participants agreed that … Continue reading






Posted in genomics, Oncology, personalized medicine, Uncategorized | Tagged , , , , | Comments Off on Circulating Biomarkers Dundee 2014 a Success!

Where are we with Targeted Cancer Therapeutics?

In a recent project, I received a draft manuscript discussing targeted cancer therapeutics and companion diagnostics in which the writer made this statement: ”CML patients in treatment with Gleevec now have the same life expectancy as people without the disease, … Continue reading

Posted in Oncology, personalized medicine | Tagged , , , , | Comments Off on Where are we with Targeted Cancer Therapeutics?

Gene Patents No More

As most of you know at this point, on Jun 13, 2013 the Supreme Court of the United States ruled essentially that native DNA sequences are not patentable subject matter.  The question ended up with the Supreme Court precisely because … Continue reading






Posted in genomics, personalized medicine | Tagged , , , , , | Comments Off on Gene Patents No More

Time to Rethink Cancer Therapy?

In an earlier post, I wondered a bit about the ultimately causes of cancer.  For the last several decades cancer has been labeled as a genetic disease, an idea which we have chased with great fervor.  Yet, It feels to … Continue reading






Posted in genomics, Oncology, personalized medicine | Tagged , , , , | Comments Off on Time to Rethink Cancer Therapy?

Lessons learned from tumor heterogeneity

My recent blog post, Tumor heterogeneity, revealed…, discussed the New England Journal of Medicine article by Gerlinger and colleagues describing the genetic heterogeneity found both within a patient’s individual tumor nodules and between spatially separate nodules.  There has been a … Continue reading






Posted in genomics, Oncology, personalized medicine, Uncategorized | Tagged , , , , , | Comments Off on Lessons learned from tumor heterogeneity

US Dept of Justice Doesn’t Like Gene Patents Either

The US Department of Justice just filed a Friend of the Court brief, in which they assert that the native sequence of human genes should not be patentable in their view.  The story was published by Genome Web this morning … Continue reading






Posted in DTC Genetic Testing, General, genomics, personalized medicine | Tagged , , , , | Comments Off on US Dept of Justice Doesn’t Like Gene Patents Either

Matching Wits with Cancer

An article and a report spurred my thinking about the complexness of the cancer cell phenotype today.  Art Levinson, the long-time CEO and now Chairman of Genentech, wrote an editorial in the 9 April 2010 issue of Science supporting changes … Continue reading






Posted in Oncology | Tagged , , , | Comments Off on Matching Wits with Cancer

Cancer Genes in the News Again

There seems to have been quite a bit of activity in the world of gene-based cancer diagnostics lately.  Just in the last 24 hours some of Myriad Genetics’ BRCA patents were ruled invalid in the United States (http://www.genomicslawreport.com/wp-content/uploads/2010/03/Myriad-SJ-Opinion.pdf) and a … Continue reading






Posted in Oncology | Tagged , , , , | Comments Off on Cancer Genes in the News Again