Category Archives: Uncategorized

Circulating Biomarkers Dundee 2014 a Success!

Circulating Biomarkers Dundee 2014 was a great success! The leadership of Ed Quazi and Elisabetta Fineschi of BioteXcel Ltd. made for a very productive two-day conference with many key leaders in the field from across the UK.  Participants agreed that … Continue reading






Posted in genomics, Oncology, personalized medicine, Uncategorized | Tagged , , , , | Comments Off on Circulating Biomarkers Dundee 2014 a Success!

FDA Tells 23andMe to Stop Marketing: Death Knell for DTC Genomics 1.0?

The FDA on Friday published a letter  addressed to 23andMe’s CEO, Anne Wojcicki, telling the company to cease marketing it’s Saliva Collection Kit and Personal Genome Service (PGS). In the letter, Alberto Gutierrez, Director of the Office of In vitro … Continue reading






Posted in DTC Genetic Testing, genomics, personalized medicine, Uncategorized | Tagged , , , , , | Comments Off on FDA Tells 23andMe to Stop Marketing: Death Knell for DTC Genomics 1.0?

Lessons learned from tumor heterogeneity

My recent blog post, Tumor heterogeneity, revealed…, discussed the New England Journal of Medicine article by Gerlinger and colleagues describing the genetic heterogeneity found both within a patient’s individual tumor nodules and between spatially separate nodules.  There has been a … Continue reading






Posted in genomics, Oncology, personalized medicine, Uncategorized | Tagged , , , , , | Comments Off on Lessons learned from tumor heterogeneity

Tumor Heterogeneity, Revealed…

A very interesting and timely article on tumor heterogeneity was published in the New England Journal of Medicine today.  Gerlinger and colleagues from the UK used next-generation sequencing to look for heterogeneity across various regions of renal tumors and metastases … Continue reading






Posted in genomics, Oncology, personalized medicine, Uncategorized | Tagged , , , | Comments Off on Tumor Heterogeneity, Revealed…

DTC Genomic Testing—What’s it good for anyways?

What is the fuss over DTC genomic/genetic testing all about anyways?  DNA is just a sequence of letters, isn’t it?  Lots of people are experiencing angst over the fact that these upstart companies would have the nerve to sequence part … Continue reading






Posted in DTC Genetic Testing, genomics, personalized medicine, Uncategorized | Tagged , , , , | Comments Off on DTC Genomic Testing—What’s it good for anyways?

Are most published research findings false?

Many people are aware of the work of John Ioannidis regarding the analysis of research findings and the conclusions drawn from those analyses.  In particular, these concepts were described by him in a paper published in PLOS Medicine in 2005 … Continue reading






Posted in Communicating Science, General, Uncategorized | Tagged , , , , | Comments Off on Are most published research findings false?

A Couple of Glimpses at the Genomic Future

There were a couple of stories in the news in the last few days regarding genomic/genetic testing that hit on recent controversies surround said testing. In earlier posts, such as this one, I commented on the now world-wide discussion about … Continue reading






Posted in DTC Genetic Testing, genomics, personalized medicine, Uncategorized | Tagged , , , , , | Comments Off on A Couple of Glimpses at the Genomic Future

DTC Genomic Testing—Policy Perspective in Science Magazine

Today’s Science magazine included a policy perspective on regulating Direct-to-Consumer genetic and genomic tests written by university ethics scholars.  In this article, the authors do a nice job of reviewing recent regulatory actions around DTC genomic testing, particularly in the … Continue reading






Posted in genomics, personalized medicine, Uncategorized | Tagged , , , | Comments Off on DTC Genomic Testing—Policy Perspective in Science Magazine

UC vs. NPG

Round two: you go, Librarians! http://www.genomeweb.com//node/942840?hq_e=el&hq_m=741462&hq_l=1&hq_v=a2a10fac80






Posted in Uncategorized | Comments Off on UC vs. NPG

Genetic Testing, Walgreen’s, and the FDA

To read some of the initial reports on the FDA’s announcement that it would like to discuss approval of Pathway Genomics’ OTC genetic tests, one might conclude the FDA acted rashly.   Since Pathway Genomics was planning to sell medical information … Continue reading






Posted in Uncategorized | Comments Off on Genetic Testing, Walgreen’s, and the FDA